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Acne is a persistent, chronic inflammatory skin condition affecting people worldwide.¹

It occurs when hair follicles beneath the skin become clogged with oil and dead skin cells. In healthy skin, sebaceous glands produce sebum, an oil that helps keep the skin from drying out. Normally, sebum exits through pores to the skin’s surface.²

In acne-prone skin, sebum and dead skin cells clog the pores. This mixture allows bacteria that normally live on the skin to grow in the clogged follicles, causing inflammation, swelling, redness, heat, and pain, which lead to outbreaks commonly called pimples.²

Pimples typically occur on the face, particularly on the forehead, nose, chin, jawline, cheeks, and hairline.4 However, they can also appear on the back, chest, and shoulders.2,3

Acne can lead to permanent complications, so it is advisable to seek help from a healthcare provider early.3 Pimples and bumps heal slowly, and as one begins to go away; others often appear.5 However, effective acne treatments are available, but the condition typically follows a prolonged course.6

References:
  1. Vasam M. et al. Acne vulgaris: A review of the pathophysiology, treatment, and recent nanotechnology-based advances. Biochemistry and Biophysics Reports 36(2023)101578.
  2. Garrick N. Acne. National Institute of Arthritis and Musculoskeletal and Skin Diseases. Published September 1, 2016. https:// www.niams.nih.gov/health- topics/acne. Accessed March, 2024
  3. Acne: Types, Causes, Treatment & Prevention. Cleveland Clinic. Available at: https://my.clevelandclinic.org/health/ diseases/12233-acne. Last access date 3-2024.
  4. Acne Face Map: The Cause of These Breakouts. Clevland Clinic. Available at: https://health.clevelandclinic.org/acne-face-map. Last access 9-2024.
  5. Mayo Clinic. Acne Symptoms and Causes. Mayo Clinic. Published October 8, 2022. https:// www.mayoclinic.org/diseases- conditions/acne/symptoms- causes/syc-20368047. Accessed March, 2024.
  6. Sutaria AH, Masood S, Saleh HM, et al. Acne Vulgaris. [Updated 2023 Aug 17]. In: Stat Pearls [Internet]. Treasure Island (FL): Stat Pearls Publishing; 2024 Jan-. Available at: https://www.ncbi.nlm.nih.gov/books/ NBK459173/.